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Coronavirus - the new strain XXIV

What is worrying about this paper is that it suggests that L452R might make Omicron more severe again *and* increase its infectiousness.

A few comments: 1. L452R was one of Delta's key mutations 2. It (& other L452 mutations) popping up in MANY diff Omicron sublineages 3. Many of the Omicron lineages L452R is in, show growth advantage over BA.2 (current dominant one) 4. Definitely one to keep a very close eye on.

https://twitter.com/chrischirp/status/1516770870269816847?cxt=HHwWnsC9gcDE04wqAAAA
 
gavreid said:
What is worrying about this paper is that it suggests that L452R might make Omicron more severe again *and* increase its infectiousness.

A few comments: 1. L452R was one of Delta's key mutations 2. It (& other L452 mutations) popping up in MANY diff Omicron sublineages 3. Many of the Omicron lineages L452R is in, show growth advantage over BA.2 (current dominant one) 4. Definitely one to keep a very close eye on.

https://twitter.com/chrischirp/status/1516770870269816847?cxt=HHwWnsC9gcDE04wqAAAA
Click to expand...

But Boris got COVID dun! :rolleyes:
 
gavreid said:
What is worrying about this paper is that it suggests that L452R might make Omicron more severe again *and* increase its infectiousness.

A few comments: 1. L452R was one of Delta's key mutations 2. It (& other L452 mutations) popping up in MANY diff Omicron sublineages 3. Many of the Omicron lineages L452R is in, show growth advantage over BA.2 (current dominant one) 4. Definitely one to keep a very close eye on.

https://twitter.com/chrischirp/status/1516770870269816847?cxt=HHwWnsC9gcDE04wqAAAA
Click to expand...

Perfect timing for a Trump appointed far right judge to cancel the mask mandate on public transit and airlines:

https://www.npr.org/2022/04/19/1093566982/florida-mask-mandate-judge-kathryn-mizelle
https://www.medpagetoday.com/infectiousdisease/covid19/98284

Just as BA2 is really getting going in the US. It is getting so tiresome having to live with these f'in morons.
 
A 31-year-old healthcare worker caught Covid twice within 20 days - the shortest-known gap between infections, Spanish researchers have claimed.

Tests show the woman was infected with two different variants - Delta in late December and then Omicron in January.

This shows that even if you have had Covid before, you can still be infected again even if fully vaccinated, the researchers say.

Reinfections in the UK require 90 days between positive tests.

https://www.bbc.co.uk/news/health-61161529
 
gavreid said:
This shows that even if you have had Covid before, you can still be infected again even if fully vaccinated, the researchers say.
Click to expand...

I havn't been following this thread closely, but having got Covid myself, it has raised my interest a bit!

I thought it was now universally understood that having had Covid in the past certainly doesn't prevent future infection, especially with a different variant. (Its what stops "herd immunity" from being a good strategy.)

But I'm not sure though on the statistics - is there data to suggest the boost given to the immune system from having recovered from Covid (on top of full vaccination record) gives at least some degree of better protection for a while at least?
 
gustavm said:
But I'm not sure though on the statistics - is there data to suggest the boost given to the immune system from having recovered from Covid (on top of full vaccination record) gives at least some degree of better protection for a while at least?
Click to expand...

There was at one time but I've not seen anything much yet re the recent omicron. I guess it will depend on the nature of the next strain.
 
No data from Scotland today 19 482 cases for what it's worth but 646 deaths (presumably we're still getting Easter coming through) and a further 1 435 admissions. Tomorrow is the last day of the school holidays.
 
19 795 cases, 284 deaths and 1 322 admissions. I think the fall off has probably been accelerated by the school holidays. Take up of vaccines in the primary school age group is very low because you can't have been infected in the previous 12 weeks so many kids will have been ineligible. We'll see what happens in May with the newer omicrons in circulation...

 
The number of people who currently have coronavirus in the UK is continuing to fall, according to new data from the Office for National Statistics (ONS).

It suggests around 3.76 million people were infected in the week ending 16 April - roughly one in 17 people.

This is a fall of about 15% on the week before - when the figure stood at 4.4 million, or around one in 15 people.

Other ONS data suggests more than 70% of people in England have had coronavirus since the pandemic began.

ONS officials welcomed the overall decline in infection in the UK in recent weeks, but warned levels of the virus remain high.

https://www.bbc.co.uk/news/health-61182159
 
gavreid said:
The number of people who currently have coronavirus in the UK is continuing to fall, according to new data from the Office for National Statistics (ONS).

It suggests around 3.76 million people were infected in the week ending 16 April - roughly one in 17 people.

This is a fall of about 15% on the week before - when the figure stood at 4.4 million, or around one in 15 people.

Other ONS data suggests more than 70% of people in England have had coronavirus since the pandemic began.

ONS officials welcomed the overall decline in infection in the UK in recent weeks, but warned levels of the virus remain high.

https://www.bbc.co.uk/news/health-61182159
Click to expand...
But do we trust the figures anymore? Tests cost ~£2/time and many may feel there is little point in self-reporting since the government appears to have lost interest anyway. On the other hand, there must be a natural limit on how many people it is possible to be infected at any one time, and we've probably previously reached that number.
 
gustavm said:
But do we trust the figures anymore? Tests cost ~£2/time and many may feel there is little point in self-reporting since the government appears to have lost interest anyway. On the other hand, there must be a natural limit on how many people it is possible to be infected at any one time, and we've probably previously reached that number.
Click to expand...

This is from the random sampling that ONS does. It's really the only measure left in place apart from testing within hospitals. Yes I think this BA.2 hit the wall in terms of maximising infections.
 
paulfromcamden said:
Looking at some of the covid charts this morning on the excellent Travelling Tabby site.

Deaths appear to be at the highest rate for 12 months - twice what they are in Ireland, EU, etc.

The overwhelming majority of deaths are amongst the elderly (80+).

https://www.travellingtabby.com/uk-coronavirus-tracker/
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Maybe somebody at the DWP has calculated that, at this rate, they’ll be able to reduce the retirement age again soon, as the draw on pensions drops :(.
 
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