I've had a problem with my MDAC today, I've always used the USB connection, a couple of times my PC has refused to talk to it, but rebooting/disconnecting/restarting DAC has fixed it, however today I could't get it to work at all.
The display said USB Ready, JRiver said it was playing but no sound was coming out, I turned everything off one thing at a time then JRiver would just crash when I hit play, despite the DAC saying USB Ready, I have a USB to SPDIF converter so I plugged that into my USB and used the MDAC coax input, this works fine. I've not tried the MDAC USB again yet as I was just happy to be able to listen to music.
My USB to SPDIF is the Matrix one so quite good and 24/192 capable, in previous listening tests I was unable to tell any difference between it and the MDACs USB input, I stopped using it as less boxes is easier, I haven't done a comparison since adding the triple Calex though.