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Coronavirus - the new strain XXI

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Seanm said:
Well, he's not in charge of the country. But I was just thinking how reasonable it all sounded!
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I'm all for listening to what Whitty has to say, unfortunately it's what our f*****t PM says that worries me.

We're already doing what we've done before. Identified there's a problem now but let's keep flying until 04:00 on Monday morning so several hundreds of potential carriers can get in - isn't this where it all started back in Jan/ Feb 2020?

Regards

Richard
 
It’s not going to be over by 2024 - the probable year of the next election. Unless emergency measures put it on hold.
 
matt j said:
Am I wrong? The genie isn't going back in the bottle, it will be a never ending stream of mutations and altered vaccines for eternity now.
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But isn't that what we have with influenza? Admittedly it's not as deadly as Covid-19, but it was at first. Better understanding, drugs and a constantly tweaked vaccine help keep it reasonably under control so much so that we don't really consider it in our daily lives, well not until we or someone we know gets very ill with it. In time I am hopeful we will get somewhere similar with Covid-19 although it remains to be seen where the mutations ultimately take us in terms of severity etc. All that said, we are going to have a rough few years for the foreseeable future. Even if Omicron turns out better than we hope there is always the chance of another nasty mutation at some point.
 
tiggers said:
But isn't that what we have with influenza? Admittedly it's not as deadly as Covid-19, but it was at first. Better understanding, drugs and a constantly tweaked vaccine help keep it reasonably under control so much so that we don't really consider it in our daily lives, well not until we or someone we know gets very ill with it. In time I am hopeful we will get somewhere similar with Covid-19 although it remains to be seen where the mutations ultimately take us in terms of severity etc. All that said, we are going to have a rough few years for the foreseeable future. Even if Omicron turns out better than we hope there is always the chance of another nasty mutation at some point.
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Yehbutt you can't mention covid and flu in the same instance, the covid police will come for you :eek:
 
matt j said:
Am I wrong? The genie isn't going back in the bottle, it will be a never ending stream of mutations and altered vaccines for eternity now.
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It will be with us for ever but at some point it won't be problem it is today - it will be manageable like 'flu or become less dangerous due to repeated exposures, like the 'common cold'.

My :( is because it could be while before we get there and I find it all quite difficult...
 
Seeker_UK said:
It will be with us for ever but at some point it won't be problem it is today - it will be manageable like 'flu or become less dangerous due to repeated exposures, like the 'common cold'.

My :( is because it could be while before we get there and I find it all quite difficult...
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I think the trick is to avoid thinking that this will bring us back to square one. We’re still most of the way through this and I can’t see big lockdowns ahead.
 
Sean,

Seanm said:
Disappointed they’ve gone for Omicron rather than Nu.
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Imagine @Tony L's disappointment as the forum's resident Neu! specialist.

Neu_albumcover.jpg


Joe
 
This is from a friend who(s) involved in coronavirus vaccine development,


A little perspective. the new variant identified in South Africa looks to have been derived from our own Alpha (B.1.1.7) which has then acquired a mutation at a site to give it the infectivity of Delta, plus various other mutations that would be expected for chronic immunosuppression (a nice cell paper showed these in a patient). This strain is more easily identified by PCR (as original Alpha was), it is more transmissible than Alpha (but so is Delta), and it may have some reduced susceptibility to antibodies (but certainly not escape). It probably is no more pathogenic than Alpha or Delta, which are little different to Wuhan wild type. Beware anyone making confident statements, save it’s more transmissible/infectious. It will be a busy time for lab scientists.

At the moment, although it is growing faster than Delta did in South Africa, I think we should be concerned about the current spread of Delta variants in Europe and elsewhere.

And beware the “Provide Update” press release. In their final analysis, Merck found that the efficacy of Molnupiravir was halved. This is probably regression to the mean – Placebo had a very high progression rate in the data up to the interim analysis. It still works, just nowhere near as well as Pfizer’s protease inhibitor.

Merck have an FDA “Ad com” next week. Should be squeaky bum time and I have bought popcorn. You can view these live . We have already approved it based on the interim data. Materials and more info are here
 
Seanm said:
This is beneath you Mull. *Maybe* border closures are the right thing to do here but there's nothing right wing or extreme about pointing out that border policy should take into account scientific evidence and advice, that the harms it does should be acknowledged and weighed against realistic benefits, that context and goals should be discussed, and that the overarching strategy should be one of international co-operation and support.

I've said it before, but we have to ask how we got ourselves into a situation where these sentiments should be interpreted as utterly wacko while panic-driven border theatre should appear as the height of reasonable common sense.
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You lost me there. Where did I give any view on the correct management of our borders? I simply pointed out that the far left to which Tony alluded, is for all prectical purposes the same as the far right. By that I meant prescriptive, authoritarian and with a liking for repressive policies, one party states and lots of control.
You are at liberty to presume other meanings..but you would be mistaken.
 
Mullardman said:
You lost me there. Where did I give any view on the correct management of our borders? I simply pointed out that the far left to which Tony alluded, is for all prectical purposes the same as the far right. By that I meant prescriptive, authoritarian and with a liking for repressive policies, one party states and lots of control.
You are at liberty to presume other meanings..but you would be mistaken.
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OK, sorry, thought you were talking about something else.
 
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