Re Quacks...picked this out of the Guardian comments section:
"Robert Lessing seems to be based on Robert Liston, a famous Scottish surgeon in the mid 19th century and first Professor of Surgery at UCL. He also bragged about his speed - allegedly amputating a leg in 2.5 minutes. Remember no anaesthetic in those days. His two most famous cases (worth the read - trust me):
1. Argument with his house-surgeon. Was the red, pulsating tumour in a small boy's neck a straightforward abscess of the skin, or a dangerous aneurism of the carotid artery? 'Pooh!' Liston exclaimed impatiently. 'Whoever heard of an aneurism in one so young?' Flashing a knife from his waistcoat pocket, he lanced it. Houseman's note – 'Out leaped arterial blood, and the boy fell.' The patient died but the artery lives, in University College Hospital pathology museum, specimen No. 1256.
2. Amputated the leg in under 2 1⁄2 minutes (the patient died afterwards in the ward from hospital gangrene; they usually did in those pre-Listerian days). He amputated in addition the fingers of his young assistant (who died afterwards in the ward from hospital gangrene). He also slashed through the coat tails of a distinguished surgical spectator, who was so terrified that the knife had pierced his vitals he dropped dead from fright.
That was the only operation in history with a 300 percent mortality."
We've watched the whole series now and every episode has a laugh out loud moment. Hope they do another series.