I think so. I didn't "get" Bob Dylan until I heard him on my current hifi. I tried him over the years on my previous rigs as well as other's rigs and never "got" him. The first time I played him on my newest rig back in '95 he suddenly clicked. Go figure...
This is my experience exactly. A great set up makes it easier to start liking different kinds of music. It makes it easier to "get" the music.
A different example: I got a demo at a high end shop some time ago. The same Cowboy Junkies song (CD) on two completely different set ups (both at least in the 8.000 UKP territory.)
First one was a Leben valve integrated with Zu Druid speakers. Sound was fantastic and everywhere! But the Cowboy Junkies sounded ... well like junkies actually! Both sound and instruments were all over the place and while it was quite a fun trip, with lots of detail (burritos?) flying around I really didn´t get the song/melody.
Next up was transistor amps from MBL (If I remember correctly) with Neat speakers. This was totally different. Not at all as trippy. The details were there but not all over. No sound to be impressed by. But I did "get" the song. It was actually a simple blues.
Now, Cowboy Junkies did indeed sound more different from other bands and genres in the Leben set up. With transistor/Neat it sounded simply ... well like a band playing a slow blues.
To sum up: I agree with Tony that a good set-up gets out of the way, but which one of the above mentioned did just that?
My notion is that the Neat system got out of the way the most.
It made the musical intention come through; it made the music sound like music and not trippy "sounds".
Maybe all great set ups in ONE regard sound exactly the same. They make music sound like music no matter the genre.
Cheers!
Lake