I’ve had some very good results from Russ Andrews’ ‘Relees’ and also from the MusicWorks anti static spray cleaner. Both seem to increase the dynamic range and I’d also say that the subtle timing cues were better after cleaning, too. The net result was that the disc became more enjoyable to listen to, the music was more interesting. Almost like a better mastering in some respects. It’s not night and day, but neither is it the sort of dancing on the head of a pin stuff you sometimes get.
My view is that it doesn’t cost a lot, nor take much time or effort, and it seems to make my system make better music, so why the hell not?
Of course, this isn’t double blind tested, nor can you revert a cleaned disc back to its pre-treatment state to double-check any observations, so what I’ve put above will, for some, not be worth the pixels it has illuminated. I merely offer it as one bloke’s anecdotal experience, in the spirit of the OP.