Daniel one thing in your reply suggests you prefer the sound coming from USB. I wonder those that square with my experience and many others using the operating system on USB. This happened when WTG sticks became available. One person used the operating system that way and reported it sounded better. Being sceptical I had no intention in implementing that.The hassle etc and I couldn't see any advantage. But running the operating system(minimal hence really only suitable for a dedicated audio pc) on USB on hearing did improve what one was hearing. You might try it if you are inclined. It would not affect your current set up but would allow you test it.Just boot from the usb stick. You can buy Sandisk Extreme 3.0 sticks for as little as £16.99 on Ebay. I would suggest trying jplay it is available on demo for free but has annoying silences(couple of seconds) to enusre if you like it in anyway you will purchase. Jplay operates by loading tracks into memory for playback and seems to prioritize audio playback. With extreme settings the PC cannot be used for anything else.Worth a try to see if these things bring improvements.
At least some of the above kinda offers suggestions to the poor rega op who has got forgotten about in the friendly exchanges on this thread
Not sure if you are aware of how transport protocols work but USB Asynchronous is undoubtedly the best for jitter reduction and is the reason why it sounds superior. Anyone who's anyone will use USB over optical (unless they have electrical noise problems or a system doesn't implement it properly). Perhaps its a good idea to start reading up on digital processing to get a basic idea how things work.
Jplay from quick glance is nothing but a system that loads files directly to ram to prevent buffer problems, this is not a issue for people who have fast enough computers that insures buffer runs as normal without problems.
People running this that don't already run a bit perfect setup (asia, wasapi) may believe this is helping but you can achieve the exact same results with running wasapi on windows with proper buffer settings and quality computer specs to support stability.