Adam,
Here's an interesting test result showing the Crosstalk / Phase noise modulation between 2 logic gates on the same silicon substrate.
The IC under test is a 74HC04 HEX logic inverters in a single package (only x2 logic gates are used in this test).
12MHz clock inputted into 1 Gate, with its output feed to the spectrum analyzer.
11.9985MHz is feed to a second logic Gate (this signal can be toggled on and off to demonstrate the phase noise modulation between between 2 gates within a single device package). There is no load on the output of this logic gate.
The 74HC04 HEX inverter is the simplest logic gate you can find - in this test only 2 logic gates are operational - imagine the phase noise effect of millions of logic gates in a typical "complex device" such as a USB input device or a integrated DAC IC.
https://dl.dropboxusercontent.com/u/86116171/12MHz Logic gate Isolation.jpg
In the above Spectrograph you can see the the phase noise caused by the second logic gate operating at a slightly different frequency - the expanse of spurie products. The Phase noise induced spurie between the two logic Gates is about -50dBc, it will be worst as the operational Frequency is increased.
At a couple of locations on the Spectrograph I turned off the second input frequency so that the second gate is silent - and you can see the clean portions on the Spectrograph with only the main 12MHz Gate toggling.
The Single Gate operating only...
https://dl.dropboxusercontent.com/u/86116171/Clean 12MHz Logic.jpg
The purpose of this test was to demonstrate how external phase noise can cross domains at the digital level - this is why Memory buffers etc. offer jitter poor isolation unless VERY VERY carefully designed - and not as an integrated solution.
Its also why its important even with an ASync DAC to insure that the USB input is as free of unwanted Phase Noise as possible - hence why I believe that the Detox is a good idea (especially when its clock-locked to the DAC's USB port's clock).