You're welcome to come and have a listen to them. To answer your questions...
1. You can position them with the 10" woofers facing inwards or outwards. You get a slightly bigger soundstage with the woofers on the outside, but this works best when the speakers are well clear of the side walls. In an asymmetrical layout with one speaker close to the side wall, you will probably get the best results with the woofers facing inwards.
2. Very little. Those drivers are only dealing with low frequencies which radiate in all directions and easily pass through furniture and other obstacles. One thing to avoid though is obstructing the vents in the side panels behind the midrange drivers. You want the sound leaving those vents to mix freely with sound escaping around the sides from the surface of the drivers, so that they cancel each other out and create a cardioid radiation pattern.
3. Surprisingly little. I have two demo rooms. I currently have them in the smaller room with about 50cm behind them. At this distance the bottom end is lifted slightly compared to the more even output you would get with the speakers in free space, which most visitors seem to enjoy. Your Trinnov ST2 will compensate for this easily and will allow you to place them even closer to the front wall, if required.
4. Including the plinths but excluding floor spikes their maximum dimensions are 33cm x 48cm x 140cm (W x D x H)
5. They sound glorious.
I don't sell Monitor Audio products. I have heard the original PL300 in the same room but not alongside the Krypton. The PL300 is an excellent loudspeaker. It might also be a better fit for your room and tastes. However, I suspect that the Krypton is the better loudspeaker in absolute terms. There is really only one other passive loudspeaker which has impressed me quite this much - the Neat Ultimatum XL10.