Covid variants: latest on the Indian, UK, South African and Brazilian variants
Updated 9 July 2021
The latest info on the Indian, UK, South African and Brazilian variants of coronavirus, including if they’re more deadly, and how they respond to vaccines.
https://www.bhf.org.uk/informations...ews/coronavirus-and-your-health/covid-variant
Is the Oxford/AstaZeneca vaccine effective against the Delta variant of coronavirus?
Yes, the Oxford/AstraZeneca vaccine is effective against the Delta variant, as long as you have both doses. A study published by Public Health England (PHE) on 22 May showed that, two weeks after the second dose, the
Oxford/AstraZeneca vaccine offered 60% protection in preventing Covid-19 illness caused by the Delta variant.
The same research, conducted between 5 April and 6 May, showed the Oxford/AstraZeneca vaccine is 33% effective against the variant three weeks after the first dose. So it’s really important to get the second dose when you get offered it.
The Oxford/AstraZeneca vaccine is even more effective when it comes to preventing severe illness caused by the Delta variant, especially after two doses. On June 14 PHE published a study showing that the Oxford/ AstraZeneca vaccine was highly effective at preventing severe disease and hospitalisation from the Delta variant of Covid-19. The study looked at emergency hospital admissions between 12 April and 4 June in England. It showed that the Oxford/ AstraZeneca vaccine was 92% effective at preventing hospitalisation with the Delta variant after two doses, and 71% effective after one dose.
Is the Oxford/Astrazeneca vaccine effective against the Alpha strain?
Research suggests that the Oxford/AstraZeneca vaccine is effective against the Alpha variant, especially after two doses.
A study published by Public Health England (PHE) on 22 May showed ,
two weeks after the second dose, the Oxford/AstraZeneca vaccine was 66% effective at preventing symptomatic cases of Covid caused by Alpha variant - well above the 50% minimum level of protection that is recommended by the World Health Organization. The same research, conducted between 5 April and 6 May, showed the vaccine was 50% effective against the variant three weeks after the first dose. So it’s really important to get the second dose when you are offered it.
Is the Oxford/AstraZeneca vaccine effective against the Beta strain?
A small study of 2,000 people in South Africa has shown that the Oxford/AstraZeneca vaccine offers minimal protection against mild cases of the Beta variant, but the vaccine is still likely to reduce severe cases and deaths from the strain.
The study, which was based people of an average age of 31, shows that protection may be as low as 10%. The research wasn’t able to determine whether it protects against serious illness or hospitalisation, because this group of people were at low risk of serious illness. Other research suggests that
the vaccine is still likely to reduce severe cases and deaths from the B.1.351 strain. More research is needed in this area.
Oxford University is working on adapting the vaccine to ensure that it protects against this variant, as well as other strains. They have said a ‘booster’ jab could be available by autumn 2021.
Is the Oxford/AstraZeneca vaccine effective against the Gamma variant of coronavirus?
Early results from lab studies show antibodies made in response to the Oxford/AstraZeneca vaccine are still active, though slightly less effective against mutations in the Gamma variant. Researchers are continuing to examine whether there is any impact on the effectiveness of the vaccine when used in real people.
The Oxford/AstraZeneca vaccine contains the genetic instructions for the whole coronavirus spike protein – different immune cells will react to different parts of the spike, producing antibodies which target different areas. This reduces the chances that any individual mutation present in new coronavirus strains will make the vaccine less effective. But researchers are continuing to examine how effective the vaccine is against the Gamma variant.