Possibly a silly one, but works for me - on several things I've built or modified for my own amusement, somewhere inside / at the psu on each rail or at each regulator is a simple cheap red LED, independent of anything in the casework/front panel. It's well worth the few mA draw simply because with the lid off, when you are fiddling with it during 'development' (or revision or repair): you can see the bloody thing is live locally. [ETA:] and while- no maybe 5v wont do you any harm - it does remind to take care probing voltages in case the probe slips and does collateral damage at an IC or similar, e.g. the risk of shorting two pins and similar non-safety-critical, but avoidable events.
(NB The LED is usually used for some other purpose too, like biasing a current source or sim. Which is where I started thinking - that was useful...)