In my view that would be one of the best setups I can think of. Two subs would be better. The great things about subs are that you can put them where they work best, and force out bass nulls leaving the mains placed suitably to create an exceptional image.
Going one step further than Mr Pig, I think you would not only lose nothing but done right you’d gain sparkle, coherence and image because of the context provided by the lows the subs would augment. If I were to start over, I’d have a pair of DIY sealed subs and something like those JRs.