Its for RF Isolation its critical to to prevent any gap that might open between the isolated sections. The wavelength of RF that can escape into the next section is determined by the largest size of the gap - any "air Gap" between the PCB and isolation walls might be tiny with wavelengths into the 10's of GHz, but a wide slot between the screws might open - this slot could be significantly wide and the resultant wavelength "low" well within our operating frequency range (think of the internal 480MHz Clock of USB PHY - in fact it will be "blind sampled" at say 3GHz to 5GHz).
Here's examples of typical high performance RF enclosures (note the multitude of screws):-
https://dl.dropboxusercontent.com/u/86116171/RF Cavty.jpg
https://dl.dropboxusercontent.com/u/86116171/RF Cavty 2.jpg
https://dl.dropboxusercontent.com/u/86116171/RF Cavty 3.jpg
https://dl.dropboxusercontent.com/u/86116171/RF Cavty 6.jpg
This is just an example of the lengths required to achieve decent isolation - when I see the other "USB Regenerators" on the market they employed no practical attempts to achieve effective RF isolation.
The Detox has x11 signal line filters to filter the RF of the signal lines between sections and input / outputs. Obviously RF filtering is also applied to the PSU lines.
The FDAC Lite will follow the same construction to isolated the Digital and Analogue stages, Clock and DAC sections etc.
Sadly the FDAC suffers from its legacy of originally "trying to squeeze it into the MDAC chassis" - its taking a lot of redesign work to repackage the design - it will be good, but shame for the "lost time" and poor initial direction ....