Typically RF tends to harden the sound and add a "Glassy" sharpness and sibilance which we tend to associate these "signatures" as sounding "Digital".
The lower Jitter tends to widened the Left / Right sound stage while firming up the systems low end, but how USB Frame packet jitter impacts the sound is very dependent on the System / DAC.
What the Detox will do remains to be "heard"
But at least I can be sure we have given the MDAC / FDAC the best quality USB signal - and in the case of the MDAC, a galvanically isolated USB port.
The USB 1.1 port with its galvanic isolation will reduce "background" noise and hum loops if present in the system when connected to the PC or when the Laptop is connected to its AC mains adaptor.
I believe that when the Spread spectrum decorrelator mode is enabled the system will lose an extra layer of hardness and sound more "Organic / Analogue".
Sorry if this sounds very vague and "HiFi babel" - but when you hear the effect for yourself then you will understand what I'm trying to describe.