I use an audioquest cinnamon usb cable between my iMac running roon core to my Cambridge audio cxn v2, can I tell the difference between the audioquest cable vs a cheap usb cable in my room with £2.5k of gik room treatment?, nope.............but that’s not the reason I upgraded the cheap usb to the audioquest cable. I upgraded to the reasonably priced cinnamon cable as it is undoubtedly manufactured to a higher quality and I have had issues with cheap cables before, not so much with reference to the sound quality but with poor connection plugs and termination issues.
So it was a decision based on build quality and the ability to fit n’ forget about it so I can sit and listen to my choice of music rather than listen to “hifi”, if I want to experiment with my sound I’ll move a gik acoustic panel a few inches to the right/left or project it out into the room another few cm - this “will” make a noticeable difference. As for cables making a noticeable difference in an untreated room?, not a discussion I need to have at this moment but never say never.......I may yet disappear down the rabbit hole in future