I don't know what 'small tweeks' Naim made, but to my ears 135's were far better sounding than the 250, although I wouldn't recommend them for difficult to drive speakers, they kept cutting out partnered with my Obelisk's if I decided to up the volume a little
You would expect them to sound better at twice the price! I've heard them many times but I've never heard a straight comparison between them and a 250. A friend uses 135s and a Klout in rotation but I think he marginally prefers the 135s. He had a 250 before and has an 82 pre.
Strange one. Years ago I went to a few Naim dems at the local dealers, Stereo Stereo in Glasgow. One of them was the original CDS I think and I happened to be there a bit early and was padding around while the Naim guys were still tweaking the system. They tried both 135 and 250 in an active system and decided to go with the 250s as they thought they sounded better. The same thing happened on the dem of something else, I can't remember what it was but they used 250s instead of 135s. I couldn't understand that at the time and still can't. I've not heard anyone who owns 135s say that they felt the 250 was better but my takaway is that they must be very close or there is no way you could prefer the 250.
If I remember correctly, the 135 has the fan, different earthing and some tightening up of the power supply. The big bits are all the same as the 250, minus a channel.
The 250 and 135s are not that powerful, the idea that they are is a myth. The 135 holds out slightly longer, it has a fan, but they both run out of puff pretty early. What I found was that the 250 got edgy and hard sounding long before the trip shut it down. I didn't have any complaints about the sound quality at lower volume but crank it up and it got nasty. With easier to drive speakers I guess it wouldn't be a problem.
The 105s are different. Yes, you've got about 40wpc more but you can still shut them down. I haven't done in for years as it takes night club volume but the main difference is that they still sound clean right up until the point where they shut down. At lower volume there is not much between them with the 105 sounding a little sweeter and more tuneful but they're very similar. I think later Meridian amps veered off a bit as you don't hear much about them but the 103 and 105s are good amps.